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One-molecule Spectroscopy
Swiss researchers demonstrated the simplest, smallest spectroscope ever: a single molecule absorbing a single photon. The experiment in quantum engineering was challenging, not only because the light needed to be at a compatible energy with the molecule, and with sufficient brightness, but also because the light had to be routed to the location of the molecule.
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Signs of Ancient Smoking
Researchers determined that the residue in a 1300-year-old Mayan flask was nicotine, and products of nicotine oxidation. A short Scientific Americanpodcast explains how the researchers combined gas chromatography, liquid chromatography, and mass spectroscopy to identify tobacco residue from inside the uncleaned container. Based on images, archeologists assumed that the Mayans smoked tobacco: now we have proof.
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Chemical Imaging of Cells
A new twist on nanospray desorption electrospray ionization (nano-DESI) with mass spectrometry lets researchers keep track of where molecules originate on the sample, with spatial resolution down to an area about 10 µm in diameter. Researchers can build chemical images of the surface, based on nano-DESI with resolution about an order of magnitude better than other online liquid extraction techniques.
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Imaging Whole Brains Faster
By automating both the tissue sectioning and fluorescence imagingrequired for 3D whole-brain imaging, researchers hope to speed up the process and make it available to more users. The Serial Two-Photon Tomography system showed half-micron resolution with the deep penetration typical of two-photon excitation. The developers used the method for several mouse-brain imaging experiments.
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Hiden Analytical Celebrates 30 YearsHiden Analytical
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LiquiPhysics ExcellenceMettler-Toledo, Inc.
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For 30 years Hiden Analytical has been a global leader in the design and manufacture of scientific instruments for research, development, and production applications. In vacuum, gas, surface, and plasma processes our quadrupole mass spectrometershave gained worldwide recognition for their precision and outstanding performance.
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Sorting Carbon Nanoparticles
It's simple to create a whole range of carbon nanoparticles, but trickier to sort the graphene from the fullerenes. The high surface activity that makes nanoparticles so interesting becomes a problem when trying to apply separation processes. Researchers recently showed that anion-exchange chromatography can divide carbon nanoparticles based on their negative charge, which corresponds to size and composition. The group is scaling up production now.
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Better Eye Diagnostics
Better resolution from a confocal adaptive optics technique brings individual retina rods into focus, as well as cones. Previous instruments used adaptive optics to correct for astigmatism, but they couldn't see the smaller light-sensing cells. Higher-resolution images will aid ophthalmic clinicians, but image processing and interpretation remain as challenges.
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Nanothermal Analysis Tackles Hard Surfaces
Nanoscale metrology on hard surfaces just acquired a new tool. The temperature-dependent properties of soft materials at scales below 100 nm can be revealed using nanoscale thermal analysis (nanoTA), an atomic force microscope-based technique. But stiff surfaces have not been easy to measure. A group of researchers has refined the technique using magnetic actuation to move the tip.
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Nanocrystallography by SEM
Crystal phase information from tiny crystals is hard to obtain but has major effects on material properties. In March, a Journal of Microscopy paper will detail ways to obtain a roughly 10-fold improvement in the ability to measure the crystal structure of nanoparticles and extremely thin films, with only a slightly modified standard scanning electron microscope (SEM).
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Ultrameter III Features Portable Lab-accurate TitrationsMyron L Company
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Color HPLC Columns — Only Available Here!Analtech, Inc.
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The Ultrameter III 9P titration kit features fast, one-touch measurements for conductivity, resistivity, TDS, ORP, free chlorine, pH and temperature and in-cell alkalinity, hardness, and LSI titrations. Alkalinity, hardness, pH, and temperature values can be manipulated in the LSI calculator to predict the effect of changes on water balance. Visit us here...
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Analtech, Inc. is now offering color High Pressure Liquid Chromatography (HPLC and UHPLC) Columns. The HPLC Columns are being offered with a wide variety of sizes and packings, from C8 and C18 silica to methyl, ethyl, butyl, phenyl, and triacontyl. In addition to the 30 variations of columns, Analtech can work with you to customize the packing.
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